Recent Publications
2023
Seok J, Cho SD, Lee J, Choi Y, Kim SY, Lee SM, Kim SH, Jeong S, Jeon M, Lee H, Kim AR, Choi B, Ha SJ, Jung I, Yoon KJ, Park JE, Kim JH, Kim BJ, Shin EC and Park SH. A virtual memory CD8+ T cell-originated subset causes alopecia areata through innate-like cytotoxicity. Nature Immunology 24(8):1308 (2023)
Jeon SH, Kang M, Jeon M, Chung Y, Kim AR, Lee YJ, Kim ES, Nam HJ, Park J, Lee JY, Shin EC, Seo SI and Park SH. CEACAM1 marks highly suppressive intratumoral regulatory T cells for targeted depletion therapy. Clinical Cancer Research 29(9):1794 (2023)
Choi SJ, Koh JY, Rha MS, Seo IH, Lee H, Jeong S, Park SH# and Shin EC#. KIR+CD8+ and NKG2A+CD8+ T cells are distinct innate-like populations in humans. Cell Reports 42(3):112236 (2023)
Seok J, Cho SD, Seo SJ and Park SH. Roles of virtual memory T cells in diseases. Immune Network 23(1):e11 (2023)
Jung YW#, Park SH# and Jun CD#. Back to the T cell: Basic and clinical application. Immune Network 23(1)e1 (2023)
Jeon SH, Lee YJ, Kim HD, Nam H, Ryoo BY, Park SH#, Joo DJ# and Shin EC#. Cancer Immunology Immunotherapy 72(2):371 (2023) #Co-corresponding author
2022
Ahn JY, Lee J, Suh YS, Song YG, Choii YJ, Lee KH, Seo SH, Song M, Oh JW, Kim M, Seo HY, Kwak JE, Youn JW, Woo JW, Shin EC, Sung YC, Park SH# and Choi JY#. Safety and immunogenicity of two recombinant DNA COVID-19 vaccines containing the coding regions of the spike or spike and nucleocapsid proteins: an interim analysis of two open-label, non-randomised, phase 1 trials in healthy adults. Lancet Microbe 3(3):E173-83 (2022) #Co-corresponding author
Kim S, Lee SW, Koh JY, Choi D, Heo M, Chung JY, Lee BH, Yang SH, Sung YC, Lee H, Shin EC and Park SH. A single administration of hIL-7-hyFc induces long-lasting T-cell expansion with maintained effector functions and TCR repertoire diversity. Blood Advances 6(23):6093 (2022)
Jung MK, Jeong SD, Noh JY, Kim DU, Jung S, Song JY, Jeong HW, Park SH# and Shin EC#. BNT162b2-induced memory T cells respond to the Omicron variant with preserved polyfunctionality. Nature Microbiology 7(6):909 (2022) #Co-corresponding author
Koh JY, Rha MS, Choi SJ, Lee HS, Han JW, Nam H, Kim DU, Lee JG, Kim MS, Park JY, Park SH#, Joo DJ# and Shin EC#. Identification of a distinct NK-like hepatic T-cell population activated by NKG2C in a TCR-independent manner. Journal of Hepatology 77(4):1059 (2022) #Co-corresponding author
Rha MS, Han JW, Koh JY, Lee HS, Kim JH, Cho K, Kim SI, Kim MS, Lee JG, Park SH, Joo DJ, Park JY and Shin EC. Impaired antibacterial response of liver sinusoidal V gamma 9(+)V delta 2(+) T cells in patients with chronic liver disease. Gut 71(3):605-15 (2022)
Choi SJ, Kim DU, Noh JY, Kim S, Park SH, Jeong HW and Shin EC. T cell epitopes in SARS-CoV-2 proteins are substantially conserved in the Omicron variant. Cell Mol Immunol 19:447-8 (2022)
Kim YI, Yu KM, Kim EH, Kim SM, Kim EJ, Casel MAB, Rollon R, Jang SG, Song MS, Park SJ, Jeong HW, Kim EG, Lee OJ, Kim YD, Choi Y, Lee SA, Choi YJ, Park SH, Jung JU and Choi YK. Age-dependent pathogenic characteristics of SARS-CoV-2 infection in ferrets. Nature Communications 13:2041 (2022)
Rha MS, Yoon YH, Koh JY, Jung JH, Lee HS, Park SK, Park SH, Kim YM, Rha KS and Shin EC. IL-17A-producing sinonasal MAIT cells in patients with chronic rhinosinusitis with nasal polyps. J Allergy and Clincial Immunology 149(2):599 (2022)
Jung S, Jung JH, Noh JY, Kim WJ, Yoon SY, Jung J, Kim ES, Kim HB, Cheong HJ, Kim WJ, Park SH, Song KH, Song JY and Shin EC. The generation of stem cell-like memory cells early after BNT162b2 vaccination is associated with durability of memory CD8(+) T cell responses. Cell Reports 40(4) (2022)
2021
Lee JS, Koh JY, Yi K, Kim YI, Park S, Kim EH, Kim SM, Park SH, Ju YS, Choi YK and Park SH. Single-cell transcriptome of bronchoalveolar lavage fluid reveals dynamic change of macrophages during SARS-CoV-2 infection in ferrets. Nature Communications 12:4567 (2021)
Jeong S, Park E, Kim HD, Sung E, Kim H, Jeon J, Kim Y, Jung UJ, Son JG, Hong Y, Lee H, Jeon M, Hwang S, Fang L, Jiang W, Wang Z, Shin EC, Park SH# and Jung J#. A novel anti-4-1BB×PD-L1 bispecific antibody augments anti-tumor immunity through tumor-directed T-cell activation and checkpoint blockade. Journal for ImmunoTherapy of Cancer 9:e002428 (2021) #Co-corresponding author
Seo IH, Eun HS, Kim JK, Lee H, Jeong S, Choi SJ, Lee J, Lee BS, Kim SH, Rou WS, Lee DH, Kim W#, Park SH# and Shin EC#. IL-15 enhances CCR5-mediated migration of memory CD8+ T cells by upregulating CCR5 expression in the absence of TCR stimulation. Cell Reports 36(4):109438 (2021) #Co-corresponding author
Kim HD, Jeong S, Park S, Lee YJ, Ju YS, Kim D, Song GW, Lee JH, Kim SY, Shin J, Shin EC, Hwang S, Yoo C and Park SH. Implication of CD69+CD103+ tissue-resident-like CD8+ T cells as a potential immunotherapeutic target for cholangiocarcinoma. Liver International 41(4):764-76 (2021)
Seo IH, Lee SJ, Noh TW, Kim JH, Joo HC, Shin EC, Park SH# and KO YG#. Increase of Vδ2+ T cells that robustly produce IL-17A in advanced abdominal aortic aneurysm tissues. Immune Network 21(2):e17 (2021) #Co-corresponding author
Han JW and Park SH. Advances in immune checkpoint inhibitors for hepatocellular carcinoma. Journal of Liver Cancer 21(2):139-45 (2021)
Jung JH, Rha MS, Sa M, Choi HK, Jeon JH, Seok H, Park DW, Park SH, Jeong HW, CHoi WS and Shin EC. SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells. Nature Communications 12:4043 (2021)
Noh JY, Kwak JE, Yang JS, Hwang SY, Yoon JG, Seong H, Hyun H, Lim CS, Yoon SY, Ryou J, Lee JY, Kim SS, Park SH, Cheong HJ, Kim WJ, Shin EC and Song JY. Longitudinal Assessment of Antisevere Acute Respiratory Syndrome Coronavirus 2 Immune Responses for Six Months Based on the Clinical Severity of Coronavirus Disease 2019. Journal of Infectious Diseases 224(5):754:63 (2021)
Noh JY, Kwak JE, Yang JS, Hwang SY, Yoon JG, Seong H, Hyun H, Lim CS, Yoon SY, Ryou J, Lee JY, Kim SS, Park SH, Cheong HJ, Kim WJ, Shin EC and Song JY. Longitudinal assessment of anti-SARS-CoV-2 immune responses for six months based on the clinical severity of COVID-19. J Infectious Diseases (2021) [Epub ahead of print]
Leem G, Cheon S, Lee H, CHoi SJ, Jeong S, Kim ES, Jeong HW, Jeong H, Park SH, Kim YS and Shin EC. Abnormality in the NK-cell population is prolonged in severe COVID-19 patients. Journal of Allergy and Clinical Immunology 148(4):996 (2021)
Cho H, Kim KH, Lee H, Kim CG, Chung H, Choi YS, Park SH, Cheong JW, Min YH, Shin EC and Kim JS. Adaptive natural killer cells facilitate effector functions of daratumumab in multiple myeloma. Clinical Cancer Research 27(10):2947-58 (2021)
Rha MS, Han JW, Koh JY, Lee HS, Kim JH, Cho K, Kim SI, Kim MS, Lee JG, Park SH, Joo DJ, Park JY and Shin EC. Impaired antibacterial response of liver sinusoidal Vγ9+Vδ2+ T cells in patients with chronic liver disease. Gut (2021) [Epub ahead of print]
Kim CG, Kim C, Yoon SE, Kim KG, Choi SJ, Kang B, Kim HR, Park SH, SHin EC, Kim YY, Kim DJ, Chung HC, Chon HJ, CHoi HJ and Lim HY. Hyperprogressive disease during PD-1 blockade in patients with advanced hepatocellular carcinoma. Journal of Hepatology 74(2) (2021)
Kim CG, Hong MH, Kim KH, Seo IH, Ahn BC, Pyo KH, Synn CB, Yoon HI, Shim HS, Lee YI, Choi SJ, Lee YJ, Kim EJ, Kim Y, Kwak JW, Jung J, Park SH, Paik S, Shin EC abd Jun HR. Dynamic changes in circulating PD-1+CD8+T lymphocytes for predicting treatment response to PD-1 blockade in patients with non-small-cell lung cancer. European Journal of Cancer 143:113-26 (2021)
Kim KH, Kim HK, Kim HD, Kim CG, Lee H, Han JW, Choi SJ, Jeong S, Heon M, Kim H, Koh J, Ku BM, Park SH, Ahn MJ, SHin EC. PD-1 blockade-unresponsive human tumor-infiltrating CD8(+) T cells are marked by loss of CD28 expression and rescued by IL-15. Cellular and Molecular Immunology 18:385-97 (2021)
Kim AR, Choi KS, Kim MS, Kim KM, Kang H, Kim S, Chowdhury T, Yu HJ, Lee CE, Lee JH, Lee ST, Won JK, Kim JW, Kim YH, Kim TM, Park SH, Choi SH, Shin EC and Park CK. Absolute quantification of tumor-infiltrating immune cells in high-grade glioma identifies prognostic and radiomics values. Cancer Immunol Immunother 70(7):1995-2008 (2021) [Epub ahead of print]
Rha MS, Jeong HW, Ko JH, Choi SJ, Seo IH, Lee JS, Sa M, Kim AR, Joo EJ, Ahn JY, Kim JH, Song KH, Kim ES, Oh DH, Ahn MY, Choi HK, Jeon JH, Choi JP, Kim HB, Kim YK, Park SH, Choi WS, Choi JY, Peck KR and Shin EC. PD-1-Expressing SARS-CoV-2-Specific CD8+ T Cells Are Not Exhausted, but Functional in Patients with COVID-19. Immunity 54(1):44-52 (2021)
Kim KH, Kim HK, Kim HD, Kim CG, Lee H, Han JW, Choi SJ, Jeong S, Jeon M, Kim H, Koh J, Ku BM, Park SH, Ahn MJ and Shin EC. PD-1 blockade-unresponsive human tumor-infiltrating CD8+ T cells are marked by loss of CD28 expression and rescued by IL-15. Cell Mol Immunol 518(2):385-97 (2021)
Han HS, Jeong S, Kim H, Kim HD, Kim AR, Kwon M, Park SH, Woo CG, Kim HK, Lee KH, Seo SP, Kang HW, Kim WT, Kim WJ, Yun SJ and Shin EC. TOX-expressing terminally exhausted tumor-infiltrating CD8+ T cells are reinvigorated by co-blockade of PD-1 and TIGIT in bladder cancer. Cancer Letter 499:137-47 (2021)
2020
Leem G, Park J, Jeon M, Kim ES, Kim SW, Lee YJ, Choi SJ, Choi B, Park S, Ju YS, Jung I, Kim S, Shin CH, Lee JY and Park SH. 4-1BB co-stimulation further enhances anti-PD-1-mediated reinvigoration of exhausted CD39+ CD8 T cells from primary and metastatic sites of epithelial ovarian cancers. Journal for ImmunoTherapy of Cancer 8(2):e001650 (2020)
Han JW, Joo DJ, Kim JH, Rh MS, Koh JY, Park HJ, Lee JG, Kim MS, Kim SI, Shin EC, Park JY and Park SH. Early reduction of regulatory T cells is associated with acute rejection in liver transplantation under tacrolimus-based immunosuppression with basiliximab induction. American Journal of Transplantation 20(8):2058-69 (2020)
Kim HD, Park S, Jeong S, Lee YJ, Lee H, Kim CG, Kim KH, Hong SM, Lee JY, Kim S, Kim HK, Min BS, Chang JH, Ju YS, Shin EC, Song GW, Hwang S and Park SH. 4-1BB delineates distinct activation status of exhausted tumor-infiltrating CD8+ T cells in hepatocellular carcinoma. Hepatology 71(3):955-71 (2020)
Rha MS, Han JW, Kim JH, Koh JY, Park HJ, Kim SI, Kim MS, Lee JG, Lee HW, Lee DH, Kim W, Park JY, Joo DJ, Park SH# and Shin EC#. Human liver CD8+ mucosal-associated invariant T cells activated by IL-15 exert TCR/MR1-independent innate-like cytotoxicity. Journal of Hepatology 73(3):640-50 (2020) #Co-corresponding author
Kim JH, Han JW, Choi YJ, Rha MS, Koh JY, Kim KH, Kim CG, Lee YJ, Kim AR, Park J, Kim HK, Min BS, Seo SI, Kang M, Park HJ, Han DH, Kim SI, Kim MS, Lee JG, Lee DH, Kim W, Park JY, Park SH#, Joo DJ# and Shin EC#. Functions of human liver CD69+CD103-CD8+ T cells depend on HIF-2α activity in healthy and pathologic livers. Journal of Hepatology 72(6):1170-81 (2020) #Co-corresponding author
Jeong S and Park SH. Co-stimulatory receptors in cancers and their implications for cancer immunotherapy. Immune Network 20(1):e3 (2020)
Son J, Cho JW, Park HJ, Moon J, Park S, Lee H, Lee J, Kim G, Park SM, Lira SA, Mckenzie AN, Kim HY, Choi CY, Lim YT, Park SY, Kim HR, Park SH, Shin EC, Lee I and Ha SJ. Tumor-Infiltrating Regulatory T-cell Accumulation in the Tumor Microenvironment Is Mediated by IL33/ST2 Signaling. Cancer Immunol Res 8(11):1393-1406 (2020)
Son SM, Woo CG, Kim DH, Yun HY, Kim H, Kim HK, Yang Y, Kwon J, Kwon M, Kim TY, Kim HD, Koh JY, Park SH, Shin EC and Han HS. Distinct tumor immune microenvironments in primary and metastatic lesions in gastric cancer patients. Scientific Reports 10(1):14293 (2020)
Kim CG, Kim C, Yoon SE, Kim KH, Choi SJ, Kang B, Kim HR, Park SH, Shin EC, Kim YY, Kim DJ, Chung HC, Chon HJ, Choi HJ and Lim HY. Hyperprogressive disease during PD-1 blockade in patients with advanced hepatocellular carcinoma. J Hepatol 74(2):350-9 (2020)
Lee JS, Park S, Jeong HW, Ahn JY, Choi SJ, Lee H, Choi B, Nam SK, Sa M, Kwon JS, Jeong SJ, Lee HK, Park SH, Park SH, Choi JY, Kim SH, Jung I and Shin EC. Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19. Science Immunology 5(49):eabd1554 (2020)
Lee SW, Choi D, Heo M, Shin EC, Park SH, Kim SJ, Oh YK, Lee BH, Yang SH, Sung YC and Lee H. hIL-7-hyFc, A Long-Acting IL-7, Increased Absolute Lymphocyte Count in Healthy Subjects. Clin Transl Sci 13(6):1161-9 (2020)
Kim AR, Han D, Choi JY, Seok J, Kim SE, Seo SH, Takahashi H, Amagai M, Park SH, Kim SC, Shin EC and Kim JH. Targeting inducible costimulator expressed on CXCR5+PD-1+ TH cells suppresses the progression of pemphigus vulgaris. J allergy Clin Immunol 145(5):1070-9 (2020)
Rha MS, Kim SW, Chang DY, Lee JK, Kim J, Park SH, Khamulratova R, Lim HS, Eun KM, Hong SN, Kim DW and Shin EC. Superantigen-related TH2 CD4+ T cells in nonasthmatic chronic rhinosinusitis with nasal polyps. J Allergy Clin Immunol. 145(5):1378-88 (2020)
Han JW, Sung PS, Hong SH, Lee H, Koh JY, Lee H, White S, Maslow JN, Weiner DB, Park SH, Jeong M, Heo J, Ahn SH, Shin EC. IFNL3-adjuvanted HCV DNA vaccine reduces regulatory T-cell frequency and increases virus-specific T-cell responses. Journal of Hepatology 73(1)72-83 (2020)
Shin EC, Han JW, Kang W, Kato T, Kim SJ, Zhong J, Kim S, Park SH, Sung PS, Watashi K, Park JY, Windisch MP, Oh JW, Wakita T, Han KH and Jang SK. The beginning of ending hepatitis C virus: A summary of the 26th International Symposium on Hepatitis C Virus and Related Viruses. Viruses 12(3). pii: E302 (2020)
Kwon M, Kim CG, Lee H, Cho H, Kim Y, Lee EC, Choi SJ, Park J, Seo IH, Bogen B, Song IC, Jo DY, Kim JS, Park SH, Choi I, Choi YS and Shin EC. PD-1 blockade reinvigorates bone marrow CD8+ T cells from patients with multiple myeloma in the presence of TGF-b inhibitors. Clinical Cancer Research 26:1644-55 (2020)
2019
Kwak JE, Kim YI, Park SJ, Yu MA, Kwon HI, Eo S, Kim TS, Cho WS, Jeong JH, Lee H, Cho Y, Kwon JA, Jeong M, Maslow JN, Kim YE, Jeon H, Kim KK, Shin EC, Song MS, Jung JE, Choi YK and Park SH. Development of a SFTSV DNA vaccine that confers complete protection against lethal infection in ferrets. Nature Communications 10:3836 (2019)
Han JW, Sung PS, Kim KH, Hong SH, Shin EC, Song MJ and Park SH. Dynamic changes in ex vivo T-cell function after viral clearance in chronic HCV infection. Journal of Infectious Diseases 220(8):1290-1301 (2019)
Kim HD and Park SH. Immunological and clinical implications of immune checkpoint blockade in human. Archives of Pharmacal Research 42(7):567-81 (2019)
Choi S, Sa M, Cho N, Kim KK and Park SH. Rbfox2 dissociation from stress granules suppresses cancer progression. Experimental & Molecular Medicine 51(4):49 (2019)
Youn JC, Jung MK, Yu HT, Kwon JS, Kwak JE, Park SH, Kim IC, Park MS, Lee SK, Choi SW, Han S, Ryu KH, Kang SM and Shin EC. Increased frequency of CD4+CD57+ senescent T cells in patients with newly diagnosed acute heart failure: exploring new pathogenic mechanisms with clinical relevance. Scientific Reports 9(1):12887 (2019)
Kim KH, Yu HT, Hwang I, Park S, Park SH, Kim SJ and Shin EC. Phenotypic and Functional Analysis of Human NK Cell Subpopulations According to the Expression of FcεRIγ and NKG2C. Frontiers in Immunology 10:2865 (2019)
Kim CG, Jang M, Kim Y, Leem G, Kim KH, Lee H, Kim TS, Choi SJ, Kim HD, Han JW, Kwon M, Kim JH, Lee AJ, Nam SK, Bae SJ, Lee SB, Shin SJ, Park SH, Ahn JB, Jung I, Lee KY, Park SH, Kim H, Min BS and Shin EC. VEGF-A drives TOX-dependent T cell exhaustion in anti-PD-1-resistant microsatellite stable colorectal cancers. Science Immunology 4(41): pii: eaay0555 (2019)
Kim CG, Kim KH, Pyo KH, Xin CF, Hong MH, Ahn BC, Kim Y, Choi SJ, Yoon HI, Lee JG, Lee CY, Park SY, Park SH, Cho BC, Shim HS, Shin EC and Kim HR. Hyperprogressive disease during PD-1/PD-L1 blockade in patients with non-small-cell lung cancer. Annals of Oncology 30(7):1104-13 (2019)
Sung PS, Park DJ, Kim JH, Han JW, Lee EB, Lee GW, Nam HC, Jang JW, Bae SH, Choi JY, Shin EC, Park SH and Yoon SK. Ex vivo detection and characterization of hepatitis B virus-specific CD8+ T cells in patients considered immune tolerant. Frontiers in Immunology 10:1319 (2019)
Park J, Kwon M, Kim KH, Kim TS, Hong SH, Kim CG, Kang SG, Moon JH, Kim EH, Park SH, Chang JH and Shin EC. Immune checkpoint inhibitor-induced reinvigoration of tumor-infiltrating CD8+ T cells is determined by their differentiation status in glioblastoma. Clinical Cancer Research 25(8):2549-59 (2019)
Kim KH, Cho J, Ku BM, Koh J, Sun JM, Lee SH, Ahn JS, Cheon J, Min YJ, Park SH, Park K, Ahn MJ and Shin EC. The first-week proliferative response of peripheral blood PD-1+CD8+ T cells predicts the response to anti-PD-1 therapy in solid tumors. Clinical Cancer Research 25(7):2144-54 (2019)
Park J, Kim CG, Shim JK, Kim JH, Lee H, Lee JE, Kim MH, Haam K, Jung I, Park SH, Chang JH, Shin EC and Kang SK. Effect of combined anti-PD-1 and temozolomide therapy in glioblastoma. OncoImmunology 8(1):e1525242 (2019)
2018
Kim HD, Song GW, Park S, Jung MK, Kim MH, Kang HJ, Yoo C, Yi K, Kim KH, Eo S, Moon DB, Hong SM, Ju YS, Shin EC, Hwang S and Park SH. Association between expression level of PD1 by tumor-infiltrating CD8 T cells and features of hepatocellular carcinoma. Gastroenterology 156(6):1884-98 (2018)
Kim MH, Kim CG, Kim SG, Shin SJ, Choe EA, Park SH#, Shin EC# and Kim J#. YAP promotes immune evasion in BRAF inhibitor-resistant melanoma by upregulating PD-L1 expression. Cancer Immunology Research 6(3):255-66 (2018) #Co-corresponding author
Kim J, Chang DY, Lee HW, Kim JH, Lee H, Sung PS, Kang W, Lee J, Shin SY, Yu HT, You S, Choi YS, Oh I, Lee DH, Lee DH, Jung MK, Suh KS, Hwang S, Kim W, Park SH#, Kim HY# and Shin EC#. Innate-like cytotoxic function of bystander activated CD8+ T cells is associated with liver injury in acute hepatitis A. Immunity 48(1):161-73 (2018) #Co-corresponding author
Kwon M, Choi YJ, Sa M, Park SH and Shin EC. Two-round mixed lymphocyte reaction for evaluation of the functional activities of anti-PD-1 and immunomodulators. Immune Network 18(6):e45 (2018)
Kim AR, Park J, Kim JH, Kwak JE, Cho Y, Lee H, Jeong M, Park SH and Shin EC. Herpes Zoster DNA vaccines with IL-7 and IL-33 molecular adjuvants elicit protective T cell immunity. Immune Network 18(5):e38 (2018)
Choi YS, Lee J, Choi SH, Lee HW, Lee JJ, Kim HJ, Ahn SH, Park SH, Huh JR, Kim HP, Park JY and Shin EC. Tumor necrosis factor-producing T-regulatory cells are associated with severe liver injury in patients with acute hepatitis A. Gastroenterology 154(4):1047-60 (2018)
Youn JC, Kim JY, Jung MK, Yu HT, Park SH, KIM IC, Lee SK, Choi WS, Han S, Ryu KH, Park S and Shin EC. Analysis of cytomegalovirus-specific T-cell responses in patients with hypertension: comparison of assay methods and antigens. Clinical Hypertension 24:5 (2018)
~2017
Yu HT, Youn JC, Kim JH, Seong YJ, Park SH, Kim HC, Lee WW, Park S and Shin EC. Arterial stiffness is associated with cytomegalovirus-specific senescent CD8+ T cells. Journal of the American Heart Association 6(9):e006535 (2017)
Jung D, Rejinold NS, Kwak JE, Park SH and Kim YC. Nano-patterning of a stainless steel microneedle surface to improve the dip-coating efficiency of a DNA vaccine and its immune response. Colloids and Surface B: Biointerfaces 159:54-61 (2017)
Park C, Choi S, Kim YE, Lee S, Park SH, Adelstein RS, Kawamoto S and Kim KK. Stress granules contain rbfox2 with cell cycle-related mRNAs. Scientific Reports 7(1):11211 (2017)
Sung PS, Lee JW, Hong SH, Park SH, Chung WJ and Shin EC. CXCL10 is produced in hepatitis A virus-infected cells in an IRF3-dependent but IFN-independent manner. Scientific Reports 7(1):6387 (2017)
Choi YJ, Kim SB, Kim JH, Park SH, Park MS, Kim JM, Han SH, Shin EC. Impaired polyfunctionality of CD8+ T cells in severe sepsis patients with human cytomegalovirus reactivation. Experimental & Molecular Medicine 19(9):e382 (2017)
Sung PS, Hong SH, Chung JH, Kim SJ, Park SH, Kim HM, Yoon SK and Shin EC. IFN-l4 potently blocks IFN-a signaling by ISG15 and USP18 in hepatitis C virus infection. Scientific Reports 7(1):3821 (2017)
Yuk CM, Park HJ, Kwon BI, Lah SJ, Chang J, Kim JY, Lee KM, Park SH, Hong S and Lee SH. Basophil-derived IL-6 regulates TH17 cell differentiation and CD4 T cell immunity. Scientific Reports 7:41744 (2017)
Shin EC#, Sung PS and Park SH#. Immune responses and immunopathology in acute and chronic viral hepatitis. Nature Reviews Immunology 16(8):509-23 (2016)
Oh IS, Textoris-Taube K, Sung PS, Kang W, Gorny X, Kahne T, Hong SH, Choi YJ, Cammann C, Naumann M, Kim JH, Park SH, Yoo OJ, Kloetzel PM, Steifert U and Shin EC. Immunoproteasome induction is suppressed in hepatitis C virus-infected cells in a protein kinase R-dependent manner. Experimental & Molecular Medicine 48(11):e270 (2016)
Kim JH, Choi YJ, Lee BH, Song MY, Ban CY, Kim J, Park J, Kim SE, Kim TG, Park SH, Kim HP, Sung YC, Kim SC and Shin EC. Programmed cell death ligand 1 alleviates psoriatic inflammation by suppressing IL-17A production from programmed cell death 1-high T cells. Journal of Allergy and Clinical Immunology 137(5):1466-76 (2016)
Oh IS and Park SH, Immune-mediated liver injury in hepatitis B virus infection. Immune Network 215(4):191-8 (2015)
Sung PS, Cheon HJ, Cho CH, Hong SH, Park DY, Seo HI, Park SH, Yoon SK, Stark GR and Shin EC. The roles of unphosphorylated-ISGF3 in HCV infection and interferon responsiveness. Proc Natl Acad Sci USA 112(33):10443-8 (2015)
Seong YJ, Sung PS, Jang YS, Choi YJ, Park BC, Park SH, Park YW and Shin EC. Activation of human natural killer cells by the soluble form of cellular prion protein. Biochemical and Biophysical Research Communications 464(2):512-8 (2015)
Kang W, Sung PS, Park SH, Chang DY, Kim S, Han KH, Kim JK, Rehermann B, Chwae YJ and Shin EC. Hepatitis C virus attenuates interferon-induced MHC class I expression to circumvent CD8+ T cell responses. Gastroenterology 146(5):1351-60 (2015)